Free NFL Betting Odds & Picks for the Seattle Seahawks vs. Buffalo Bills week 15 matchup. The Seahawks are a 5 point road favorite. The over/under is 42.5. Dave reminds us defensively the Bills have been nothing special – disappointing especially since Mario Williams was brought in to transform the culture. For Seattle Sidney Rice has stepped up his game and Golden Tate looks like the perfect big-play compliment for the offense.