LIONS vs. 49ers (Sept 16 8:20 PM ET)

Could the 49ers look any better in Week 1? I do no think so, as they beat the Packers in Green Bay and they looked fantastic on both sides of the ball. Alex Smith outplayed Aaron Rodgers and the 49ers may have an offense that may stack up with their stacked defense.

The Lions won their season opener and while Matt Stafford passed for 355 yards he only had 1 TD and 3 INT. He, Calvin Johnson, and the Detroit passing offense will have to have to carry the offense, as not only do the 49ers have the best run defense in the league, but the Lions have one of the worst rushing offenses in the NFL.

The Lions played good defense in their win over the Rams, but it is the Lambs and they will not be able to stop the new offensive minded 49ers. Also, the San Fran D will play well and the Lions will not score a lot of points. The 49ers will win and win convincingly.